Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting
- Creator: Chauhan, Ganesh , Adams, Hieab H. H. , Satizabal, Claudia L. , Bis, Joshua C. , Teumer, Alexander , Sargurupremraj, Muralidharan , Hofer, Edith , Trompet, Stella , Hilal, Saima , Smith, Albert Vernon , Jian, Xueqiu , Malik, Rainer , Traylor, Matthew , Pulit, Sara L. , Amouyel, Philippe , Mazoyer, Bernard , Zhu, Yi-Cheung , Kaffashian, Sara , Schilling, Sabrina , Beecham, Gary W. , Montine, Thomas J. , Schellenberg, G. D. , Kjartansson, O. , Guðnason, V. , Knopman, D. S. , Griswold, M. E. , Windham, B. G. , Gottesman, R. F. , Mosley, T. H. , Schmidt, R. , Saba, Y. , Schmidt, H. , Takeuchi, F. , Yamaguchi, S. , Nabika, T. , Kato, N , Rajan, K. B. , Aggarwal, N. T. , De Jager, P. L. , Evans, D. A. , Psaty, B M. , Rotter, J. I. , Rice, K. , Lopez, O. L. , Liao, J. , Chen, C. , Cheng, C.Y. , Wong, T. Y. , Ikram, M. K. , van der Lee, S. J. , Amin, N. , Chouraki, V. , Destefano, A. L. , Aparicio, H. J. , Romero, J. R. , Maillard, P. , Decarli, C. , Wardlaw, J. M. , Del C. Valdés Hernández, M. , Luciano, M. , Liewald, D. , Deary, I. J. , Starr, J. M. , Bastin, M. E. , Maniega, S. M. , Slagboom, P. E. , Beekman, M. , Deelen, J. , Uh, H. W. , Lemmens, R. , Brodaty, H. , Wright, MJ. , Ames, D. , Boncoraglio, G. B. , Hopewell, J. C. , Beecham, A. H. , Blanton, S. H. , Wright, C. B. , Sacco, R. L. , Wen, W. , Thalamuthu, A. , Armstrong, N. J. , Chong, E. , Schofield, P. R. , Kwok, J. B. , van der Grond, J. , Stott, D. J. , Ford, I. , Jukema, J. W. , Vernooij, M. W. , Hofman, A. , Uitterlinden, A. G. , van der Lugt, A. , Wittfeld, K. , Grabe, H. J. , Hosten, N. , von Sarnowski, B. , Völker, U. , Levi, Christopher , Jimenez-Conde, J. , Sharma, P. , Sudlow, C. L. M. , Rosand, J. , Woo, D. , Cole, J. W. , Mechia, J. F. , Slowik, A. , Thijs, V. , Lindgren, A. , Melander, O. , Grewal, R. P. , Rundek, T. , Rexrode, K. , Arnett, D. K. , Jern, C. , Johnson, J. A. , Benavente, O. R. , Asselbergs, F. R. , Srikanth, V. , Thomson, R. , McWhirter, R. , Moran, C. , Callisaya, M. , Phan, T. , Rutten-Jacobs, L. C. A. , Bevan, S. , Tzourio, C. , Mather, K. A. , Sachdev, P. S. , van Duijn, C. M. , Worrall, B. B. , Dichgans, M. , Kittner, S. J. , Markus, H. S. , Ikram, M. A. , Fornage, M. , Launer, L. J. , Seshadri, S. , Longstreth, W. T. , Debette, S.
- Resource Type: journal article
- Date: 2019
Analysis of shared heritability in common disorders of the brain
- Creator: Anttila, Verneri , Bulik-Sullivan, Brendan , Patsopoulos, Nikolaos A. , Ripke, Stephan , Wei, Zhi , Yu, Dongmei , Lee, Phil H. , Turley, Patrick , Grenier-Boley, Benjamin , Chouraki, Vincent , Kamatani, Yoichiro , Berr, Claudine , Finucane, Hilary K. , Holliday, Elizabeth , Attia, John , Cairns, Murray , Loughland, Carmel , Schall, Ulrich , Henskens, Frans , Scott, Rodney , Reitz, C , Goate, AM , Huentelman, MJ , Walters, Raymond K. , Ilyas Kamboh, M , Larson, EB , Rogaeva, E , George-Hyslop, PS , Hakonarson, H , Kukull, WA , Farrer, LA , Barnes, LL , Beach, TG , Yesim Demirci, F , Bras, Jose , Head, E , Hulette, CM , Jicha, GA , Kauwe, JSK , Kaye, JA , Leverenz, JB , Levey, AI , Lieberman, AP , Pankratz, VS , Poon, WW , Duncan, Laramie , Quinn, JF , Saykin, AJ , Schneider, LS , Smith, AG , Escott-Price, Valentina , Falcone, Guido J. , Gormley, Padhraig , Malik, Rainer
- Resource Type: journal article
- Date: 2018
Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke
- Creator: Cole, John W. , Xu, Huichun , Ryan, Kathleen , Jaworek, Thomas , Dueker, Nicole , McArdle, Patrick , Gaynor, Brady , Cheng, Yu-Ching , O'Connell, Jeffrey , Bevan, Steve , Malik, Rainer , Ahmed, Naveed Uddin , Amouyel, Philippe , Anjum, Sheraz , Bis, Joshua C. , Crosslin, David , Danesh, John , Engelter, Stefan T. , Fornage, Myriam , Frossard, Philippe , Holliday, Elizabeth , Levi, Christopher
- Resource Type: journal article
- Date: 2018
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
- Creator: Malik, Rainer , Chauhan, Ganesh , Anderson, Christopher D. , Chong, Michael , Adams, Hieab H. H. , Ago, Tetsuro , Almgren, Peter , Amouyel, Philippe , Ay, Hakan , Bartz, Traci M. , Benavente, Oscar R. , Bevan, Steve , Traylor, Matthew , Holliday, Elizabeth G. , Attia, John , Levi, Christopher R. , Carrera, C , Carty, CL , Chasman, DI , Chen, W-M , Cole, JW , Correa, A , Cotlarciuc, I , Sargurupremraj, Muralidharan , Cruchaga, C , Danesh, J , de Bakker, PIW , DeStefano, AL , Den Hoed, M , Duan, Q , Engelter, ST , Falcone, GJ , Gottesman, RF , Grewal, RP , Okada, Yukinori , Gudnason, V , Gustafsson, S , Haessler, J , Harris, TB , Hassan, A , Havulinna, AS , Heckbert, SR , Holliday, EG , Howard, G , Hsu, F-C , Mishra, Aniket , Hyacinth, HI , Ikram, MA , Ingelsson, E , Irvin, MR , Jian, X , Jiménez-Conde, J , Johnson, JA , Jukema, JW , Kanai, M , Keene, KL , Rutten-Jacobs, Loes , Kissela, BM , Kleindorfer, DO , Kooperberg, C , Kubo, M , Lange, LA , Langefeld, CD , Langenberg, C , Launer, LJ , Lee, J-M , Lemmens, R , Giese, Anne-Katrin , van der Laan, Sander W. , Gretarsdottir, Solveig
- Resource Type: journal article
- Date: 2018
Common coding variant in SERPINA1 increases the risk for large artery stroke
- Creator: Malik, Rainer , Cardenas, IF , Rothwell, PM , Levi, C , Attia, J , Sudlow, CLM , Braun, D , Markus, HS , Wintrode, PL , Berger, K , Jenne, DE , Dichgans, M , Dau, Therese , Seixas, Susana , Bevan, Steve , Lincz, Lisa F. , Holliday, Elizabeth G. , Burgess, Annette I. , Rannikmäe, Kristiina , Minnerup, Jens , Kriebel, Jennifer , Waldenberger, Melanie , Müller-Nurasyid, Martina , Gonik, Maria , Levi, Christopher , Attia, John , Maguire, Jane , Sivakumar, Anirudh , Deredge, Daniel J. , Edeleva, Evgeniia V. , Götzfried, Jessica , van der Laan, Sander W. , Pasterkamp, Gerard , Beaufort, Nathalie
- Resource Type: journal article
- Date: 2017
Genetic variation at 16q24.2 is associated with small vessel stroke
- Creator: Traylor, Matthew , Malik, Rainer , Yet, Idil , Spector, Tim D. , Bell, Jordana T. , Hannon, Ellis , Mill, Jonathan , Chauhan, Ganesh , Debette, Stephanie , Bis, Joshua C. , Longstreth, W. T. , Ikram, M. Arfan , Nalls, Mike A. , Levi, Chris , Cotlarciuc, Iona , Radmanesh, Farid , Thorleifsson, Gudmar , Hanscombe, Ken B. , Langefeld, Carl , Saleheen, Danish , Rost, Natalia S.
- Resource Type: journal article
- Date: 2017
Genetic associations with white matter hyperintensities confer risk of lacunar stroke
- Creator: Traylor, Matthew , Rutten-Jacobs, Loes C. A. , Dichgans, Martin , Markus, Hugh S. , Thijs, Vincent , Holliday, Elizabeth G. , Levi, Chris , Bevan, Steve , Malik, Rainer , Boncoraglio, Giorgio , Sudlow, Cathie , Rothwell, Peter M.
- Resource Type: journal article
- Date: 2016
Genome-wide association analysis of young-onset stroke identifies a locus on chromosome 10q25 near HABP2
- Creator: Cheng, Yu-Ching , Stanne, Tara M. , Cole, John W. , O'Connell, Jeffrey R. , Danesh, John , Rasheed, Asif , Zhao, Wei , Engelter, Stefan , Grond-Ginsbach, Caspar , Kamatani, Yoichiro , Lathrop, Mark , Leys, Didier , Giese, Anne-Katrin , Levi, Christopher , Ho, Weang Kee , Traylor, Matthew , Amouyel, Philippe , Holliday, Elizabeth G. , Malik, Rainer , Xu, Huichun , Kittner, Steven J.
- Resource Type: journal article
- Date: 2016
Low-frequency and common genetic variation in ischemic stroke: the METASTROKE collaboration
- Creator: Malik, Rainer , Traylor, Matthew , Battey, Thomas W. K. , Berger, Klaus , Boncoraglio, Giorgio B. , Chauhan, Ganesh , Cheng, Yu-Ching , Chen, Wei-Min , Clarke, Robert , Cotlarciuc, Ioana , Debette, Stephanie , Falcone, Guido J. , Pulit, Sara L. , Levi, Christopher R. , Bevan, Steve , Hopewell, Jemma C. , Holliday, Elizabeth G. , Zhao, Wei , Abrantes, Patricia , Amouyel, Philippe , Attia, John R.
- Resource Type: journal article
- Date: 2016
Differences in common genetic predisposition to ischemic stroke by age and sex
- Creator: Traylor, Matthew , Rutten-Jacobs, Loes C. A. , Dichgans, Martin , Levi, Chris , Lewis, Cathryn M. , Markus, Hugh S. , Holliday, Elizabeth G. , Malik, Rainer , Sudlow, Cathie , Rothwell, Peter M. , Maguire, Jane M. , Koblar, Simon A. , Bevan, Steve , Boncoraglio, Giorgio
- Resource Type: journal article
- Date: 2015
Genetic overlap between diagnostic subtypes of ischemic stroke
- Creator: Holliday, Elizabeth G. , Traylor, Matthew , Boncoraglio, Giorgio B. , Clarke, Robert , Cole, John W. , Fornage, Myriam , Furie, Karen L. , Ikram, M. Arfan , Jannes, Jim , Kittner, Steven J. , Lincz, Lisa F. , Maguire, Jane M. , Malik, Rainer , Oldmeadow, Christopher , Scott, Rodney J. , Levi, Christopher , Attia, John , Bevan, Steve , Falcone, Guido , Hopewell, Jemma C. , Cheng, Yu-Ching , Cotlarciuc, Ioana , Bis, Joshua C. , Boerwinkle, Eric
- Resource Type: journal article
- Date: 2015
No additional prognostic value of genetic information in the prediction of vascular events after cerebral ischemia of arterial origin: The PROMISe study
- Creator: Achterberg, Sefanja , Kappelle, L. Jaap , Mali, W.P.T.M. , Doevendans, P.A. , Farrall, Martin , Holliday, Elizabeth G. , Sudlow, Cathie , Hopewell, Jemma C. , Cheng, Yu-Ching , Fornage, Myriam , Ikram, M. Arfan , Malik, Rainer , De Bakker, Paul I. W. , Bevan, Steve , Thorsteinsdottir, Unnur , DeStefano, Anita L. , Worrall, Bradford B. , Reiner, Alex P. , Mitchell, Braxtin D. , Clarke, Robert , Levi, Christopher , Seshadri, Sudha , Boncoraglio, Giorgio B. , Traylor, Matthew , Sharma, Pankaj , Bis, Joshua C. , Gretarsdottir, Solveig , Psaty, Bruce M. , Rothwell, Peter M. , Rosand, Jonathan , Meschia, James F. , Stefansson, Kari , Dichgans, Martin , Markus, Hugh S. , Algra, Ale , Van Der Graaf, Y. , Grobbee, D.E. , Rutten, G.E.H.M. , Visseren, F.L.J. , Moll, F.L.
- Resource Type: journal article
- Date: 2015
Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants
- Creator: Malik, Rainer , Freilinger, Tobias , Bis, Joshua C. , Hopewell, Jemma C. , Ferrari, Michel D. , Rannikmae, Kristiina , Wessman, Maija , Kallela, Mikko , Kubisch, Christian , Fornage, Myriam , Meschia, James F. , Lehtimäki, Terho , Winsvold, Bendik S. , Sudlow, Cathie , Clarke, Robert , Chasman, Daniel I. , Mitchell, Braxton D. , Maguire, Jane , Kaprio, Jakko , Farrall, Martin , Raitakari, Olli T. , Kurth, Tobias , Ikram, M. Arfan , Anttila, Verneri , Reiner, Alex P. , Longstreth, W. T. , Rothwell, Peter M. , Strachan, David P. , Sharma, Pankaj , Seshadri, Sudha , Quaye, Lydia , Cherkas, Lynn , Schürks, Markus , Rosand, Jonathan , Vander Heiden, Jason , Ligthart, Lannie , Boncoraglio, Giorgio B. , Davey Smith, George , van Duijn, Cornelia M. , Stefansson, Kari , Worrall, Bradford B. , Nyholt, Dale R. , Markus, Hugh S. , van den Maagdenberg, Arn M. J. M. , Cotsapas, Chris , Traylor, Matthew , Zwart, John A. , Palotie, Aarno , Dichgans, Martin , de Vries, Boukje , Holliday, Elizabeth G. , Terwindt, Gisela M. , Sturm, Jonathan
- Resource Type: journal article
- Date: 2015
A novel MMP12 locus Is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach
- Creator: Traylor, Matthew , Mäkelä, Kari-Matti , Malik, Rainer , Sudlow, Cathie , Bevan, Steve , Raitoharju, Emma , Oksala, Niku , Thijs, Vincent , Lemmens, Robin , Lindgren, Arne , Slowik, Agnieszka , Kilarski, Laura L. , Maguire, Jane M. , Walters, Matthew , Algra, Ale , Sharma, Pankaj , Attia, John R. , Boncoraglio, Giorgio B. , Rothwell, Peter M. , de Bakker, Paul I. W. , Bis, Joshua C. , Saleheen, Danish , Holliday, ELizabeth G. , Kittner, Steven J. , Mitchell, Braxton D. , Rosand, Jonathan , Meschia, James F. , Levi, Christopher , Dichgans, Martin , Lehtimäki, Terho , Lewis, Cathryn M. , Markus, Hugh S. , Devan, William J. , Nalls, Mike A. , Wiggins, Kerri L. , Zhao, Wei , Cheng, Yu-Ching , Achterberg, Sefanja
- Resource Type: journal article
- Date: 2014
Effect of genetic variants associated with plasma homocysteine levels on stroke risk
- Creator: Cotlarciuc, Iona , Malik, Rainer , Markus, Hugh S. , Rosand, Jonathan , Mitchell, Braxton D. , Kittner, Steven J. , Meschia, James F. , van Meurs, Joyce B. J. , Uitterlinden, Andre G. , Worrall, Bradford B. , Dichgans, Martin , Sharma, Pankaj , Holliday, Elizabeth G. , Ahmadi, Kourosh R. , Paré, Guillaume , Psaty, Bruce M. , Fornage, Myriam , Hasan, Nazeeha , Rinne, Paul E. , Ikram, M. Arfan
- Resource Type: journal article
- Date: 2014
Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12
- Creator: Kilarski, Laura L. , Achterberg, Sefanja , Walters, Matthew , Worrall, Bradford B. , Sale, Michele M. , Algra, Ale , Kappelle, L. Jaap , Wijmenga, Cisca , Norrving, Bo , Sandling, Johanna K. , Röennblom, Lars , Goris, An , Devan, William J. , Franke, Andre , Sudlow, Cathie , Rothwell, Peter M. , Levi, Christopher , Holliday, Elizabeth G. , Fornage, Myriam , Psaty, Bruce , Gretarsdottir, Solveig , Thorsteinsdottir, Unnar , Seshadri, Sudha , Traylor, Matthew , Mitchell, Braxton D. , Kittner, Steven , Clarke, Robert , Hopewell, Jemma C. , Bis, Joshua C. , Boncoraglio, Giorgio B. , Meschia, James , Ikram, M. Arfan , Hansen, Bjorn M. , Montaner, Joan , Malik, Rainer , Thorleifsson, Gudmar , Stefanson, Kari , Rosand, Jonathan , de Bakker, Paul I. W. , Farrall, Martin , Dichgans, Martin , Markus, Hugh S. , Bevan, Steve , Lindgren, Arne , Pare, Guillame , Sharma, Pankaj , Slowik, Agniescka , Thijs, Vincent
- Resource Type: journal article
- Date: 2014
Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies
- Creator: Malik, Rainer , Bevan, Steve , de Stefano, Anita L. , Fornage, Myriam , Psaty, Bruce M. , Ikram, M. Afran , Launer, Lenore J. , Van Duijn, Cornelia M. , Sharma, Pankaj , Mitchell, Braxton D. , Rosand, Jonathan , Meschia, James F. , Nalls, Michael A. , Levi, Christopher , Rothwell, Peter M. , Sudlow, Cathie , Markus, Hugh S. , Seshadri, Sudha , Dichgans, Martin , MD Wellcome Trust Case Control Consortium 2, , Holliday, Elizabeth G. , Devan, William J. , Cheng, Yu-Ching , Ibrahim-Verbaas, Carla A. , Verhaaren, Benjamin F. J. , Bis, Joshua C. , Joon, Aron Y.
- Resource Type: journal article
- Date: 2014
Polygenic overlap between kidney function and large artery atherosclerotic stroke
- Creator: Holliday, Elizabeth G. , Traylor, Matthew , Sudlow, Cathie , Rothwell, Peter M. , Coresh, Josef , Hamet, Pavel , Tremblay, Johanne , Turner, Stephen T. , de Andrade, Mariza , Rao, Madhumathi , Schmidt, Reinhold , Crick, Peter A. , Malik, Rainer , Robino, Antonietta , Peralta, Carmen A. , Jukema, J. Wouter , Mitchell, Paul , Rosas, Silvia E. , Wang, Jie Jin , Scott, Rodney J. , Dichgans, Martin , Mitchell, Braxton D. , Kao, W. H. Linda , Bevan, Stephen , Fox, Caroline S. , Levi, Christopher , Attia, John , Markus, Hugh S. , Maguire, Jane , Koblar, Simon A. , Sturm, Jonathan , Hankey, Graeme J. , Oldmeadow, Christopher , McEvoy, Mark
- Resource Type: journal article
- Date: 2014
Shared genetic susceptibility to ischemic stroke and coronary artery disease : a genome-wide analysis of common variants
- Creator: Dichgans, Martin , Malik, Rainer , Ódonnell, Christopher J. , Fornage, Myriam , Thorsteinsdottir, Unnur , Psaty, Bruce M. , Hengstenberg, Christian , Seshadri, Sudha , Erdmann, Jeanette , Bis, Joshua C. , Peters, Annette , Boncoraglio, Giorgio B. , König, Inke R. , März, Winfred , Meschia, James F. , Kathiresan, Sekar , Ikram, M. Arfan , McPherson, Ruth , Stefansson, Kari , Sudlow, Cathie , Reilly, Muredach , Thompson, John R. , Sharma, Pankaj , Rosand, Jonathon , Hopewell, Jemma C. , Chambers, John C. , Watkins, Hugh , Rothwell, Peter M. , Roberts, Robert , Markus, Hugh S. , Samani, Nilesh J. , Farrall, Martin , Schunkert, Heribert , Clarke, Robert , Gretarsdottir, Solveig , Thorleifsson, Gudmar , Mitchell, Branxton D. , Assimes, Themistocles L. , Levi, Christopher
- Resource Type: journal article
- Date: 2014
17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status
- Creator: Adib-Samii, Poneh , Rost, Natalia , Gschwendtner, Andreas , Malik, Rainer , Richie, Alexa , Gamble, Dale , Segal, Helen , Parati, Eugenio A. , Ciusani, Emilio , Holliday, Elizabeth G. , Maguire, Jane , Wardlaw, Joanna , Traylor, Matthew , Worrall, Bradford , Bis, Joshua , Wiggins, Kerri L. , Longstreth, Will , Kittner, Steve J. , Cheng, Yu-Ching , Mosley, Thomas , Falcone, Guido J. , Furie, Karen L. , Leiva-Salinas, Carlos , Devan, William , Lau, Benison C. , Saleem Khan, Muhammed , Australian Stroke Genetics Collaborative , Wellcome Trust Case-Control Consortium-2 , METASTROKE , Sharma, Pankaj , Fornage, Miriam , Mitchell, Braxton D. , Psaty, Bruce M. , Sudlow, Cathie , Biffi, Alessandro , Levi, Christopher , Boncoraglio, Giorgio B. , Rothwell, Peter M. , Meschia, James , Dichgans, Martin , Rosand, Jonathan , Markus, Hugh S. , Lanfranconi, Silvia , Fitzpatrick, Kaitlin , Bevan, Steve , Kanakis, Allison , Valant, Valerie
- Resource Type: journal article
- Date: 2013